EST secretome analysis of burrowing nematode – Radopholus similis

Abstract

Sangeetha K, Babu RO, Eapen SJ., EST secretome analysis of burrowing nematode – Radopholus similis, Online J Bioinform., Plant parasitic nematodes excrete or secrete (ES) various types of molecules in host plants. The secretome of Radopholus similis could identify drug targets and biomarkers for diagnostics or nematode survival factors. Patterns of gene annotation and functional diversity of excretory/secretory proteins of burrowing nematode (R. similis) were determined. Two hundred fourteen secretory proteins of R similis were identified. Forty six percent of gene ontology terms were associated with biological processes, 38% with molecular function and 16% with cellular components. InterProScan revealed EGF and IGFBP like domains. The role of hypothetical proteins involved in signaling, metabolic and degradative pathways and those preserved for R. similis species are described.